MSM: Secret Agent for Joint Health

Methylsulfonylmethane (MSM) is a unique ingredient that offers great benefits for the joints even when already in the arthritic state. All of the biochemical properties of MSM are not fully understood, but, it has some interesting benefits for canine and horse joint health. Regardless of its benefits though, MSM is curiously absent in many joint supplements.

MSM is a sulfur containing natural compound found in many green plants. While there are multiple studies regarding MSM, its most convincing evidence is with use for arthritis. MSM acts as an anti inflammatory and as a hydrating, waste-removal machine in the body. It is the perfect compliment to Glucosamine and Chondroitin, which feed the joint tissues (glycosaminoglycans). 

horse joint xray

3 Benefits of MSM

1. Improves Flexibility

Research has shown that MSM is highly effective in improving joint flexibility via the restoration of the hydration of tissue. This is important for horses and dogs to remain active and mobile.

2. Normalizes Inflammation Response

MSM has powerful anti-inflammatory properties due to its ability to allow metabolic wastes to be removed from the cells. In short, animals with inflammation pain may experience less pain when provided MSM to the diet.

3. Detoxifies the Body

One of the most important features of MSM is that it makes the cells more permeable. MSM serves to move toxins and metabolic waste products out of the cells, while essential nutrients and hydration can be moved in.

We believe MSM should be included in all joint formulas and serves to be part of the "Big 3" natural nutrients for joint health. Together with glucosamine sulfate and chondroitin sulfate, Nusentia®’s RJX formulations contain significant, therapeutic dosages of MSM. This liquid formula has help countless dogs and horses back to mobility.


Pearson TW, Dawson HJ, Lackey HB. Natural occurring levels of dimethyl sulfoxide in selected fruits, vegetables, grains, and beverages. J Agric Food Chem 1981;29:1089-1091.

Marañón G, Muñoz-Escassi B, Manley W, et al. The effect of methyl sulphonyl methane supplementation on biomarkers of oxidative stress in sport horses following jumping exercise. Acta Vet Scand . 2008;50:45.

Beilke MA, Collins-Lech C, Sohnle PG. Effects of dimethyl sulfoxide on the oxidative function of human neutrophils. J Lab Clin Med 1987;110:91-96.

arthritis glucosamine horses joints msm rjx horses

← Older Post Newer Post →

Leave a comment

Please note, comments must be approved before they are published

Pet Nutrition


RJX® for Dogs
Triple strength non-steroidal liquid for canine joint support, protection, and regeneration.


joint support dogs

acl age aging allergies allergy medicine allergy season animal digest antibiotics anxiety apple cider vinegar arthritis bacteria bad breath bee stings benefits biting bladder breath calm cancer cat cat illness cat vitamins cats celavin chews coat cognitive comparisons constipation crate dehydrated dental depression dermatitis dermix dha diabetes diarrhea diet digestion digestive digestive enzymes digestive remedies dog food dog vitamins dogs dosage dreaming efa enzyme deficiency enzyme miracle enzymes epi essential fatty acids exercise exocrine pancreatic insufficiency fatty acids feline fish oil flatulence fleas freeze dried freeze dried dog food fur loss gas gastrointestinal gi gi health glucosamine golden retriever grain free grain free diet grass eating grooming gsd gut gut health hair loss halitosis health hind leg home remedies home renedies horses hot spots IBS immune system incontinence inflammation injury insect bites intestine itchy joints kidney lameness lawn burns leaky gut lifestyle liver damage loose stool malnutrition medicine miracle pack miraclezyme missing fur mood msm mushy poop myths natural remedies nutrition obesity odor omega-3 pancreas pancreatic pancreatitis paw licking pet care pet vitamins pets picky eater popular prednisone probiotic miracle probiotics product comparison puppy raw raw dog food remedy rjx rjx horses routine sbo season seasonal senior dog shedding shy dog sick skin and coat socializing stool eating strength stress supplementation supplements symptoms systemic enzymes tear stains teeth tendons timid dog tips training tylosin tzl uri urinary urine stains uti utrin vitamin depletion vitamins wellness yeast yogurt